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WHAT
IN
Scientist I Analytical Development
Job
Vertex Pharmaceuticals
US
-
San Diego,
California
Job Code - 1057BR
Position - FULL TIME
Job First Active on: Sunday, November 01, 2009
APPLY TO THIS JOB (You will be applying directly to Vertex Pharmaceuticals for this position!)
JOB DESCRIPTION: Scientist I (Analytical Development)
Vertex Pharmaceuticals Incorporated is a global biotechnology company committed to the discovery and development of breakthrough small molecule drugs for serious diseases. The Company's strategy is to commercialize its products both independently and in collaboration with major pharmaceutical companies. Vertex's product pipeline is focused on viral diseases, cystic fibrosis, inflammation, autoimmune diseases, cancer, and pain. Vertex co-discovered the HIV protease inhibitor, Lexiva, with GlaxoSmithKline.
We are seeking a talented individual to join our Analytical Development group in San Diego, CA. The successful candidate will have demonstrated an ability to discover, design and implement new analytical techniques for quantitative and qualitative analyses of low-level impurities in pharmaceutical drug substances and drug products. Responsibilities will include identification and characterization of impurities using Thermo LTQ-Orbitrap, Agilent triple quadrupole mass spectrometers, and other analytical instruments. The ideal candidate will provide isolation of low-level, small molecule impurities and degradants utilizing mass triggered fraction collection on preparative LC/MS or other instruments. Additional responsibilities will include method development and method validation for trace impurity analyses by LC/MS/MS, GC/MS or other techniques.
REQUIREMENTS - QUALIFICATIONS: Scientist I (Analytical Development)
· Requires a PhD degree in Chemistry and 1+ years of relevant experience; or MS degree in Chemistry and 3+ years of relevant experience; or a BS degree in Chemistry and 6+ years of relevant experience.
· Must have a natural products, analytical chemistry or synthetic organic chemistry background.
· Strong knowledge of modern analytical chemistry techniques including separation techniques and mass spectrometry experience is required.
· Familiarity with Agilent and Thermo Mass spectrometry instrumentation and software is desirable.
· Previous pharmaceutical industry experience would be preferred.
· Must be highly self-motivated, highly productive with strong problem solving skills and be capable of working both independently and in a collaborative interdepartmental setting.
· Strong written and verbal communication as well as interpersonal skills are a must.
Vertex Pharmaceuticals
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